Ontology highlight
ABSTRACT:
SUBMITTER: Zhao Y
PROVIDER: S-EPMC5622227 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Zhao Yingjie Y Yun Dapeng D Zou Xiang X Jiang Tao T Li Gang G Hu Lingna L Chen Juxiang J Xu Jianfeng J Mao Ying Y Chen Hongyan H Lu Daru D
American journal of cancer research 20170901 9
In this study, we conducted a genome-wide scan of single nucleotide polymorphisms (SNPs) to identify coding variants that is associated with the risk of glioblastoma (GBM), the most common and most malignant subtype of glioma. We genotyped 1038 GBM cases and 1008 controls in a Chinese Han population using Illumina HumanExome Beadchip v1.0. A missense variant, rs8957 (E[GAG]233D[GAU], SLC2A4RG, 20q13.33), was found being associated with GBM risk, with an odd ratio (OR) of 1.43 (95% confidence int ...[more]