Ontology highlight
ABSTRACT: Background and purpose
Sex and race disparities in recombinant tissue plasminogen activator (rt-PA) use have been reported. We sought to explore sex and race differences in the utilization of rt-PA at primary stroke centers (PSCs) compared to non-PSCs across the US.Methods
Data from the National (Nationwide) Inpatient Sample (NIS) 2004-2010 was utilized to assess sex differences in treatment for ischemic stroke in PSCs compared to non-PSCs.Results
There were 304,152 hospitalizations with a primary diagnosis of ischemic stroke between 2004 and 2010 in the analysis: 75,160 (24.7%) patients were evaluated at a PSC. A little over half of the patients evaluated at PSCs were female (53.8%). A lower proportion of women than men received rt-PA at both PSCs (6.8 vs. 7.5%, p?p?p-value for interaction?=?0.58).Conclusion
Women are less likely to receive rt-PA than men at both PSCs and non-PSCs. Absolute treatment rates are lowest in black women, although the relative difference in men and women was greatest for white women.
SUBMITTER: Boehme AK
PROVIDER: S-EPMC5623663 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Boehme Amelia K AK Carr Brendan G BG Kasner Scott Eric SE Albright Karen C KC Kallan Michael J MJ Elkind Mitchell S V MSV Branas Charles C CC Mullen Michael T MT
Frontiers in neurology 20170927
<h4>Background and purpose</h4>Sex and race disparities in recombinant tissue plasminogen activator (rt-PA) use have been reported. We sought to explore sex and race differences in the utilization of rt-PA at primary stroke centers (PSCs) compared to non-PSCs across the US.<h4>Methods</h4>Data from the National (Nationwide) Inpatient Sample (NIS) 2004-2010 was utilized to assess sex differences in treatment for ischemic stroke in PSCs compared to non-PSCs.<h4>Results</h4>There were 304,152 hospi ...[more]