Ontology highlight
ABSTRACT:
SUBMITTER: Refaai MA
PROVIDER: S-EPMC5625753 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Refaai Majed A MA Kothari Truptesh H TH Straub Shana S Falcon Jacob J Sarode Ravi R Goldstein Joshua N JN Brainsky Andres A Omert Laurel L Lee Martin L ML Milling Truman J TJ
Emergency medicine international 20170919
<h4>Introduction</h4>To investigate the impact of a 4-factor prothrombin complex concentrate (4F-PCC [Beriplex®/Kcentra®]) versus plasma on "time to procedure" in patients with acute/severe gastrointestinal bleeding requiring rapid vitamin K antagonist (VKA) reversal prior to invasive procedure.<h4>Methods</h4>A post hoc analysis of two phase III trials of 4F-PCC versus plasma in patients with acute/severe gastrointestinal bleeding. The treatment arms were compared for study treatment volume, in ...[more]