Multicellular Vascularized Engineered Tissues through User-Programmable Biomaterial Photodegradation.
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ABSTRACT:
SUBMITTER: Arakawa CK
PROVIDER: S-EPMC5628157 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
Multicellular Vascularized Engineered Tissues through User-Programmable Biomaterial Photodegradation.
Arakawa Christopher K CK Badeau Barry A BA Zheng Ying Y DeForest Cole A CA
Advanced materials (Deerfield Beach, Fla.) 20170724 37
A photodegradable material-based approach to generate endothelialized 3D vascular networks within cell-laden hydrogel biomaterials is introduced. Exploiting multiphoton lithography, microchannel networks spanning nearly all size scales of native human vasculature are readily generated with unprecedented user-defined 4D control. Intraluminal channel architectures of synthetic vessels are fully customizable, providing new opportunities for next-generation microfluidics and directed cell function. ...[more]
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