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ABSTRACT: Objectives
The objective of this study was to compare occupational variation of the risk of bladder cancer in the Nordic countries and Canada.Methods
In the Nordic Occupational Cancer study (NOCCA), 73?653 bladder cancer cases were observed during follow-up of 141.6?million person-years. In the Canadian Census Health and Environment Cohort (CanCHEC), 8170 cases were observed during the follow-up of?36.7 million person-years. Standardised incidence ratios with 95% CI were estimated for 53 occupations in the NOCCA cohort and HR with 95% CIs were estimated for 42 occupations in the CanCHEC.Results
Elevated risks of bladder cancer were observed among hairdressers, printers, sales workers, plumbers, painters, miners and laundry workers. Teachers and agricultural workers had reduced risk of bladder cancer in both cohorts. Chimney-sweeps, tobacco workers and waiters had about 1.5-fold risk in the Nordic countries; no risk estimates for these categories were given from the CanCHEC cohort.Conclusion
We observed different occupational patterns in risk of bladder cancer in Nordic countries and Canada. The only occupation with similarly increased risk was observed among sales workers. Differences in smoking across occupational groups may explain some, but not all, of this variation.
SUBMITTER: Hadkhale K
PROVIDER: S-EPMC5629726 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Hadkhale Kishor K MacLeod Jill J Demers Paul A PA Martinsen Jan Ivar JI Weiderpass Elisabete E Kjaerheim Kristina K Lynge Elsebeth E Sparen Pär P Tryggvadottir Laufey L Anne Harris M M Tjepkema Michael M Peters Paul A PA Pukkala Eero E
BMJ open 20170804 8
<h4>Objectives</h4>The objective of this study was to compare occupational variation of the risk of bladder cancer in the Nordic countries and Canada.<h4>Methods</h4>In the Nordic Occupational Cancer study (NOCCA), 73 653 bladder cancer cases were observed during follow-up of 141.6 million person-years. In the Canadian Census Health and Environment Cohort (CanCHEC), 8170 cases were observed during the follow-up of 36.7 million person-years. Standardised incidence ratios with 95% CI were estimate ...[more]