Ontology highlight
ABSTRACT:
SUBMITTER: Nemecek D
PROVIDER: S-EPMC5633033 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Němeček David D Dvořáková Markéta M Heroutová Ivona I Chmelíková Eva E Sedmíková Markéta M
PeerJ 20171006
If fertilization of matured oocyte does not occur, unfertilized oocyte undergoes aging, resulting in a time-dependent reduction of the oocyte's quality. The aging of porcine oocytes can lead to apoptosis. Carbon monoxide (CO), a signal molecule produced by the heme oxygenase (HO), possesses cytoprotective and anti-apoptotic effects that have been described in somatic cells. However, the effects of CO in oocytes have yet to be investigated. By immunocytochemistry method we detected that both isof ...[more]