Ontology highlight
ABSTRACT:
SUBMITTER: Lee HW
PROVIDER: S-EPMC5633313 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Lee Hye Won HW Park Won-Jin WJ Heo Yu-Ran YR Park Tae In TI Park Soo Young SY Lee Jae-Ho JH
OncoTargets and therapy 20171003
Telomere length is associated with the development of hepatocellular carcinoma (HCC), and recent studies have focused on the genetic alteration or polymorphism in telomere-maintaining genes. We examined the clinicopathologic and prognostic value of rs401681 polymorphism, located in the <i>TERT-CLPTM1L</i> locus, in HCC. The relationship between rs401681 variants and telomere length was also analyzed in 156 HCC patients. The rs401681 polymorphism had the following genotype frequencies: C/C in 51. ...[more]