A Comparative Analysis of Genetic Ancestry and Admixture in the Colombian Populations of Choco and Medellin.

ABSTRACT: At least 20% of Colombians identify as having African ancestry, yielding the second largest population of Afro-descendants in Latin America. To date, there have been relatively few studies focused on the genetic ancestry of Afro-Latino populations. We report a comparative analysis of the genetic ancestry of Chocó, a state located on Colombia's Pacific coast with a population that is >80% Afro-Colombian. We compared genome-wide patterns of genetic ancestry and admixture for Chocó to six other admixed American populations, with an emphasis on a Mestizo population from the nearby Colombian city of Medellín. One hundred sample donors from Chocó were genotyped across 610,545 genomic sites and compared with 94 publicly available whole genome sequences from Medellín. At the continental level, Cho

SUBMITTER: Conley AB 

PROVIDER: S-EPMC5633392 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature