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Revealing the genomic differences between two subgroups in Lactobacillus gasseri.

ABSTRACT: Being an autochthonous species in humans, Lactobacillus gasseri is widely used as a probiotic for fermented products. We thoroughly compared the gene contents of 75 L. gasseri genomes and identified two intraspecific groups by the average nucleotide identity (ANI) threshold of 94%. Group I, with 48 strains, possessed 53 group-specific genes including the gassericin T cluster (9 genes) and N-acyl homoserine lactone lactonase. Group II, with 27 strains, including the type strain ATCC 33323, possessed group-specific genes with plasmid- or phage-related annotations. The genomic differences provide evidences for demarcating a new probiotic group within L. gasseri.

SUBMITTER: Tada I

PROVIDER: S-EPMC5633531 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Revealing the genomic differences between two subgroups in Lactobacillus gasseri.

Tada Ipputa I Tanizawa Yasuhiro Y Endo Akihito A Tohno Masanori M Arita Masanori M

Bioscience of microbiota, food and health 20170801 4

Being an autochthonous species in humans, Lactobacillus gasseri is widely used as a probiotic for fermented products. We thoroughly compared the gene contents of 75 L. gasseri genomes and identified two intraspecific groups by the average nucleotide identity (ANI) threshold of 94%. Group I, with 48 strains, possessed 53 group-specific genes including the gassericin T cluster (9 genes) and N-acyl homoserine lactone lactonase. Group II, with 27 strains, including the type stra ...[more]

PMID: 29038772

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