Ontology highlight
ABSTRACT:
SUBMITTER: Renz BW
PROVIDER: S-EPMC5635789 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Renz Bernhard W BW D'Haese Jan G JG Werner Jens J Westphalen C Benedikt CB Ilmer Matthias M
Medical sciences (Basel, Switzerland) 20170619 2
The diagnosis of pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis, in particular, when patients present with unresectable disease. While significant progress has been made in understanding the biology of PDAC, this knowledge has not translated into a clear clinical benefit and current chemotherapeutic strategies only offer a modest improvement in overall survival. Accordingly, novel approaches are desperately needed. One hypothesis that could-at least in part-explain the desola ...[more]