Friction forces position the neural anlage.
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ABSTRACT:
SUBMITTER: Smutny M
PROVIDER: S-EPMC5635970 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Publications
Friction forces position the neural anlage.
Smutny Michael M Ákos Zsuzsa Z Grigolon Silvia S Shamipour Shayan S Ruprecht Verena V Čapek Daniel D Behrndt Martin M Papusheva Ekaterina E Tada Masazumi M Hof Björn B Vicsek Tamás T Salbreux Guillaume G Heisenberg Carl-Philipp CP
Nature cell biology 20170327 4
During embryonic development, mechanical forces are essential for cellular rearrangements driving tissue morphogenesis. Here, we show that in the early zebrafish embryo, friction forces are generated at the interface between anterior axial mesoderm (prechordal plate, ppl) progenitors migrating towards the animal pole and neurectoderm progenitors moving in the opposite direction towards the vegetal pole of the embryo. These friction forces lead to global rearrangement of cells within the neurecto ...[more]
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