Ontology highlight
ABSTRACT:
SUBMITTER: Santin JM
PROVIDER: S-EPMC5636609 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Santin Joseph M JM Vallejo Mauricio M Hartzler Lynn K LK
eLife 20170915
Neural systems use homeostatic plasticity to maintain normal brain functions and to prevent abnormal activity. Surprisingly, homeostatic mechanisms that regulate circuit output have mainly been demonstrated during artificial and/or pathological perturbations. Natural, physiological scenarios that activate these stabilizing mechanisms in neural networks of mature animals remain elusive. To establish the extent to which a naturally inactive circuit engages mechanisms of homeostatic plasticity, we ...[more]