Ontology highlight
ABSTRACT:
SUBMITTER: Csiszar A
PROVIDER: S-EPMC5636770 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
GeroScience 20170829 4
Hypertension in the elderly substantially increases both the risk of vascular cognitive impairment (VCI) and Alzheimer's disease (AD); however, the underlying mechanisms are not completely understood. This review discusses the effects of hypertension on structural and functional integrity of cerebral microcirculation, including hypertension-induced alterations in neurovascular coupling responses, cellular and molecular mechanisms involved in microvascular damage (capillary rarefaction, blood-bra ...[more]