Ontology highlight
ABSTRACT:
SUBMITTER: Zhang K
PROVIDER: S-EPMC5637461 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Chemical science 20170818 10
Chemically functionalized and nanostructured materials, which mimic the features of the natural extracellular matrix, provide a tool to organize cell surface receptors into nanoscale clusters and manipulate cell functions. However, the existing materials are mainly based on static structures. Herein, we developed a DNA based structure-switchable and multivalent material that acts as a 'nano-spring', enabling reversible control of membrane receptor function at the cell surface. This 'nano-spring' ...[more]