Dataset Information
Infant BMI peak as a predictor of overweight and obesity at age 2 years in a Chinese community-based cohort.
Ontology highlight
ABSTRACT: Objectives
Infant body mass index (BMI) peak has proven to be a useful indicator for predicting childhood obesity risk in American and European populations. However, it has not been assessed in China. We characterised infant BMI trajectories in a Chinese longitudinal cohort and evaluated whether BMI peak can predict overweight and obesity at age 2 years.Methods
Serial measurements (n=6-12) of weight and length were taken from healthy term infants (n=2073) in a birth cohort established in urban Shanghai. Measurements were used to estimate BMI growth curves from birth to 13.5 months using a polynomial regression model. BMI peak characteristics, including age (in months) and magnitude (BMI, in kg/m2) at peak and prepeak velocities (in kg/m2/month), were estimated. The relationship between infant BMI peak and childhood BMI at age 2 years was examined using binary logistic analysis.Results
Mean age at peak BMI was 7.61 months, with a magnitude of 18.33?kg/m2. Boys (n=1022) had a higher average peak BMI (18.60 vs 18.07?kg/m2, p<0.001) and earlier average achievement of peak value (7.54 vs 7.67 months, p<0.05) than girls (n=1051). With 1?kg/m2 increase in peak BMI and 1?month increase in peak time, the risk of overweight at age 2 years increased by 2.11 times (OR 3.11; 95%?CI 2.64 to 3.66) and 35% (OR 1.35; 95%?CI 1.21 to 1.50), respectively. Similarly, higher BMI magnitude (OR 2.69; 95%?CI 2.00 to 3.61) and later timing of infant BMI peak (OR 1.35; 95%?CI 1.08 to 1.68) were associated with an increased risk of childhood obesity at age 2 years.Conclusions
We have shown that infant BMI peak is valuable for predicting early childhood overweight and obesity in urban Shanghai. Because this is the first Chinese community-based cohort study of this nature, future research is required to examine infant populations in other areas of China.
SUBMITTER: Sun J
PROVIDER: S-EPMC5640041 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
Infant BMI peak as a predictor of overweight and obesity at age 2 years in a Chinese community-based cohort.
BMJ open 20171006 10
<h4>Objectives</h4>Infant body mass index (BMI) peak has proven to be a useful indicator for predicting childhood obesity risk in American and European populations. However, it has not been assessed in China. We characterised infant BMI trajectories in a Chinese longitudinal cohort and evaluated whether BMI peak can predict overweight and obesity at age 2 years.<h4>Methods</h4>Serial measurements (n=6-12) of weight and length were taken from healthy term infants (n=2073) in a birth cohort establ ...[more]