Ontology highlight
ABSTRACT:
SUBMITTER: Wu Z
PROVIDER: S-EPMC5641103 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Wu Zehua Z Zhu Xiangying X Xu Wendi W Zhang Yu Y Chen Lin L Qiu Fabo F Zhang Binyuan B Wu Liqun L Peng Zhihai Z Tang Huamei H
Oncotarget 20170627 42
Colon cancer is one of the major causes of cancer mortality worldwide. However, the underlying mechanism and therapeutic targets of colon cancer have not yet been fully elucidated. In the present study, we demonstrate that citron rho-interacting, serine/threonine kinase 21 (CIT) promotes the growth of human colon cancer cells. CIT is overexpressed in human colon cancer tissues and cell lines. High expression of CIT predicts poor survival for patients with colon cancer. In colon cancer cells, CIT ...[more]