Ontology highlight
ABSTRACT:
SUBMITTER: Brand C
PROVIDER: S-EPMC5641912 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
ChemistryOpen 20170807 5
Here, we report a method to specifically bind liposomal radiopharmaceuticals to a CoCrMo alloy, which can be used in arterial stents, via an irreversible inverse electron-demand Diels-Alder reaction. Inspired by recent accomplishments in pre-targeted imaging using tetrazine-<i>trans</i>-cyclooctene click chemistry, we synthesized <sup>89</sup>Zr-labeled <i>trans</i>-cyclooctene-functionalized liposomal nanoparticles, which were validated on a tetrazine-appended polydopamine-coated CoCrMo surface ...[more]