Ontology highlight
ABSTRACT:
SUBMITTER: van Erp AEM
PROVIDER: S-EPMC5642642 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
van Erp Anke E M AEM Versleijen-Jonkers Yvonne M H YMH Hillebrandt-Roeffen Melissa H S MHS van Houdt Laurens L Gorris Mark A J MAJ van Dam Laura S LS Mentzel Thomas T Weidema Marije E ME Savci-Heijink C Dilara CD Desar Ingrid M E IME Merks Hans H M HHM van Noesel Max M MM Shipley Janet J van der Graaf Winette T A WTA Flucke Uta E UE Meyer-Wentrup Friederike A G FAG
Oncotarget 20170707 41
In order to explore the potential of immune checkpoint blockade in sarcoma, we investigated expression and clinical relevance of programmed cell death-1 (PD-1), programmed death ligand-1 (PD-L1) and CD8 in tumors of 208 sarcoma patients. Primary untreated osteosarcoma (<i>n</i> = 46), Ewing sarcoma (<i>n</i> = 32), alveolar rhabdomyosarcoma (<i>n</i> = 20), embryonal rhabdomyosarcoma (<i>n</i> = 77), synovial sarcoma (<i>n</i> = 22) and desmoplastic small round cell tumors (DSRCT) (<i>n</i> = 11 ...[more]