Ontology highlight
ABSTRACT:
SUBMITTER: Sofat N
PROVIDER: S-EPMC5644551 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Sofat Nidhi N Harrison Abiola A Russell Mark D MD Ayis Salma S Kiely Patrick D PD Baker Emma H EH Barrick Thomas Richard TR Howe Franklyn A FA
Journal of pain research 20171010
Osteoarthritis (OA) is the most prevalent arthritis worldwide and is characterized by chronic pain and impaired physical function. We hypothesized that heightened pain in hand OA could be reduced with duloxetine or pregabalin. In this prospective, randomized clinical study, we recruited 65 participants, aged 40-75 years, with a Numerical Rating Scale (NRS) for pain of at least 5. Participants were randomized to one of the following three groups: duloxetine, pregabalin, and placebo. The primary e ...[more]