Ontology highlight
ABSTRACT:
SUBMITTER: South AM
PROVIDER: S-EPMC5645786 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
South Andrew M AM Maestretti Lynn L Kambham Neeraja N Grimm Paul C PC Chaudhuri Abanti A
Pediatric transplantation 20170822 7
Pediatric renal transplant recipient survival continues to improve, but ABMR remains a significant contributor to graft loss. ABMR prognostic factors to guide treatment are lacking. C4d staining on biopsies, diagnostic of ABMR, is associated with graft failure. Persistent C4d+ on follow-up biopsies has unknown significance, but could be associated with worse outcomes. We evaluated a retrospective cohort of 17 pediatric renal transplant patients diagnosed with ABMR. Primary outcome at 12 months w ...[more]