Ontology highlight
ABSTRACT:
SUBMITTER: Lao Y
PROVIDER: S-EPMC5647404 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Lao Yuanxiang Y Li Yanyan Y Hou Yufang Y Chen Huahai H Qiu Bintao B Lin Weiran W Sun Aihua A Wei Handong H Jiang Ying Y He Fuchu F
Scientific reports 20171018 1
Sinusoidal dedifferentiation is a complicated process induced by several factors, and exists in early stage of diverse liver diseases. The mechanism of sinusoidal dedifferentiation is poorly unknown. In this study, we established a NaAsO<sub>2</sub>-induced sinusoidal dedifferentiation mice model. Liver sinusoidal endothelial cells were isolated and isobaric tag for relative and absolute quantitation (iTRAQ) based proteomic approach was adopted to globally examine the effects of arsenic on liver ...[more]