Ontology highlight
ABSTRACT:
SUBMITTER: Skinner OS
PROVIDER: S-EPMC5647560 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Skinner Owen S OS McAnally Michael O MO Van Duyne Richard P RP Schatz George C GC Breuker Kathrin K Compton Philip D PD Kelleher Neil L NL
Analytical chemistry 20171004 20
Native electron capture dissociation (NECD) is a process during which proteins undergo fragmentation similar to that from radical dissociation methods, but without the addition of exogenous electrons. However, after three initial reports of NECD from the cytochrome c dimer complex, no further evidence of the effect has been published. Here, we report NECD behavior from horse spleen ferritin, a ∼490 kDa protein complex ∼20-fold larger than the previously studied cytochrome c dimer. Application of ...[more]