Ontology highlight
ABSTRACT:
SUBMITTER: Clements DR
PROVIDER: S-EPMC5648240 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Clements Derek R DR Murphy John Patrick JP Sterea Andra A Kennedy Barry E BE Kim Youra Y Helson Erin E Almasi Shekoufeh S Holay Namit N Konda Prathyusha P Paulo Joao A JA Sharif Tanveer T Lee Patrick W PW Weekes Michael P MP Gygi Steven P SP Gujar Shashi S
Journal of proteome research 20170823 9
Myeloid cells play a central role in the context of viral eradication, yet precisely how these cells differentiate throughout the course of acute infections is poorly understood. In this study, we have developed a novel quantitative temporal in vivo proteomics (QTiPs) platform to capture proteomic signatures of temporally transitioning virus-driven myeloid cells directly in situ, thus taking into consideration host-virus interactions throughout the course of an infection. QTiPs, in combination w ...[more]