Ontology highlight
ABSTRACT:
SUBMITTER: Gordon CM
PROVIDER: S-EPMC5650062 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Gordon Catherine M CM Gordon Leslie B LB Snyder Brian D BD Nazarian Ara A Quinn Nicolle N Huh Susanna S Giobbie-Hurder Anita A Neuberg Donna D Cleveland Robert R Kleinman Monica M Miller David T DT Kieran Mark W MW
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110701 7
Hutchinson-Gilford progeria syndrome (HGPS) is a rare segmental premature aging disorder that affects bone and body composition, among other tissues. We sought to determine whether bone density and structural geometry are altered in children with HGPS and whether relationships exist among these parameters and measures of skeletal anthropometry, body composition, and nutrition. We prospectively enrolled 26 children with HGPS (ages 3.1 to 16.2 years). Outcomes included anthropometric data; bone ag ...[more]