Ontology highlight
ABSTRACT:
SUBMITTER: Yu Y
PROVIDER: S-EPMC5650418 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Yu Yan Y Lu Bingjian B Lu Weiguo W Li Shuang S Li Xiuqin X Wang Xinyu X Wan Xiaoyun X Chen Yaxia Y Feng Suwen S Jia Yao Y Yang Ru R Tang Fangxu F Li Xiong X Zhang Shulan S Wang Xinyan X Wei Heng H Peng Zhilan Z Lu Lin L Zhong Huizhen H Zhao Linjun L Huang Zhangqian Z Lin Lin L Shen Weihong W Lu Yan Y Cao Zhu Z Zou Jian J Ma Yuejiang Y Chen Xiaojing X Tian Qifang Q Lu Shiming S Liu Pengyuan P Ma Ding D Xie Xing X Cheng Xiaodong X
Oncotarget 20170908 43
Complete hydatidiform mole (CHM) is a rare pregnancy-related disease with invasive potential. The genetics underlying the sporadic form of CHM have not been addressed previously, but maternal genetic variants may be involved in biparental CHM. We performed whole-exome sequencing of 51 patients with CHM and 47 healthy women to identify genetic variants associated with CHM. In addition, candidate variants were analyzed using single base extension and Matrix Assisted Laser Desorption/Ionization-Tim ...[more]