Ontology highlight
ABSTRACT:
SUBMITTER: Hedeker D
PROVIDER: S-EPMC5650580 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Hedeker Donald D du Toit Stephen H C SHC Demirtas Hakan H Gibbons Robert D RD
Biometrics 20170420 1
This article discusses marginalization of the regression parameters in mixed models for correlated binary outcomes. As is well known, the regression parameters in such models have the "subject-specific" (SS) or conditional interpretation, in contrast to the "population-averaged" (PA) or marginal estimates that represent the unconditional covariate effects. We describe an approach using numerical quadrature to obtain PA estimates from their SS counterparts in models with multiple random effects. ...[more]