Ontology highlight
ABSTRACT:
SUBMITTER: Xu C
PROVIDER: S-EPMC5652732 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Xu Cheng C Liu Xiaoqing X Geng Yibo Y Bai Qingran Q Pan Changcun C Sun Yu Y Chen Xin X Yu Hai H Wu Yuliang Y Zhang Peng P Wu Wenhao W Wang Yu Y Wu Zhen Z Zhang Junting J Wang Zhaohui Z Yang Rui R Lewis Jenna J Bigner Darell D Zhao Fangping F He Yiping Y Yan Hai H Shen Qin Q Zhang Liwei L
Oncotarget 20170728 44
Diffuse intrinsic pontine glioma (DIPG) is a devastating brain tumor, with a median survival of less than one year. Due to enormous difficulties in the acquisition of DIPG specimens and the sophisticated technique required to perform brainstem orthotopic injection, only a handful of DIPG pre-clinical models are available. In this study, we successfully established eight patient-derived DIPG cell lines, mostly derived from treatment-naïve surgery or biopsy specimens. These patient-derived cell li ...[more]