Ontology highlight
ABSTRACT:
SUBMITTER: Zai CC
PROVIDER: S-EPMC5653224 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Zai Clement C CC Tiwari Arun K AK Chowdhury Nabilah I NI Brandl Eva J EJ Shaikh Sajid A SA Freeman Natalie N Lieberman Jeffrey A JA Meltzer Herbert Y HY Kennedy James L JL Müller Daniel J DJ
Neuropsychobiology 20160101 3
<h4>Background</h4>Schizophrenia (SCZ) is a chronic severe neuropsychiatric disorder, where pharmacological treatment has been hindered by adverse effects, including antipsychotic-induced weight gain (AIWG) and related complications. Genetic studies have been exploring the appetite regulation and energy homeostasis pathways in AIWG with some promising leads. The serotonin system has been shown to participate in these pathways.<h4>Methods</h4>In the current study, we examined single nucleotide po ...[more]