Ontology highlight
ABSTRACT:
SUBMITTER: Titiz AS
PROVIDER: S-EPMC5655155 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Titiz Ali S AS Hill Michael R H MRH Mankin Emily A EA M Aghajan Zahra Z Eliashiv Dawn D Tchemodanov Natalia N Maoz Uri U Stern John J Tran Michelle E ME Schuette Peter P Behnke Eric E Suthana Nanthia A NA Fried Itzhak I
eLife 20171024
The hippocampus is critical for episodic memory, and synaptic changes induced by long-term potentiation (LTP) are thought to underlie memory formation. In rodents, hippocampal LTP may be induced through electrical stimulation of the perforant path. To test whether similar techniques could improve episodic memory in humans, we implemented a microstimulation technique that allowed delivery of low-current electrical stimulation via 100 <i>μm</i>-diameter microelectrodes. As thirteen neurosurgical p ...[more]