Ontology highlight
ABSTRACT:
SUBMITTER: Gantz I
PROVIDER: S-EPMC5655696 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Gantz Ira I Okamoto Taro T Ito Yuka Y Okuyama Kotoba K O'Neill Edward A EA Kaufman Keith D KD Engel Samuel S SS Lai Eseng E
Diabetes, obesity & metabolism 20170706 11
<h4>Aims</h4>To assess the safety and efficacy of omarigliptin in Japanese patients with type 2 diabetes (T2D).<h4>Methods</h4>In a 24-week double-blind trial, 414 patients with T2D were randomized to omarigliptin 25 mg once weekly, sitagliptin 50 mg once daily or placebo. The double-blind period was followed by a 28-week open-label extension during which all patients received omarigliptin 25 mg once weekly. Efficacy endpoints were glycated haemoglobin (HbA1c), 2-hour postprandial glucose (PPG) ...[more]