Risk factors and pregnancy outcomes associated with placental malaria in a prospective cohort of Papua New Guinean women.

ABSTRACT:

Background

Plasmodium falciparum in pregnancy results in substantial poor health outcomes for both mother and child, particularly in young, primigravid mothers who are at greatest risk of placental malaria (PM) infection. Complications of PM include maternal anaemia, low birth weight and preterm delivery, which contribute to maternal and infant morbidity and mortality in coastal Papua New Guinea (PNG).

Methods

Placental biopsies were examined from 1451 pregnant women who were enrolled in a malaria prevention study at 14-26 weeks gestation. Clinical and demographic information were collected at first antenatal clinic visits and women were followed until delivery. Placental biopsies were collected and examined for PM using histology. The presence of infected erythrocytes and/o

SUBMITTER: Lufele E 

PROVIDER: S-EPMC5655867 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature