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Suppression of male courtship by a Drosophila pheromone receptor.

ABSTRACT: In male Drosophila, chemosensory cues control many aspects of social behavior. We found that males with a mutated Gustatory receptor 32a gene (Gr32a) show high courtship toward males and mated females, indicating that GR32a functions as a pheromone receptor for a male inhibitory pheromone. Notably, we discovered that tarsal Gr32a-expressing neurons were essential for courtship suppression and projected to the ventrolateral protocerebrum, implying direct communication of chemosensory neurons with a higher-order brain structure.

SUBMITTER: Miyamoto T

PROVIDER: S-EPMC5655991 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature

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Suppression of male courtship by a Drosophila pheromone receptor.

Miyamoto Tetsuya T Amrein Hubert H

Nature neuroscience 20080720 8

In male Drosophila, chemosensory cues control many aspects of social behavior. We found that males with a mutated Gustatory receptor 32a gene (Gr32a) show high courtship toward males and mated females, indicating that GR32a functions as a pheromone receptor for a male inhibitory pheromone. Notably, we discovered that tarsal Gr32a-expressing neurons were essential for courtship suppression and projected to the ventrolateral protocerebrum, implying direct communication of chemosensory neurons with ...[more]

PMID: 18641642

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