Ontology highlight
ABSTRACT:
SUBMITTER: Markov AV
PROVIDER: S-EPMC5656677 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Markov Andrey V AV Sen'kova Alexandra V AV Warszycki Dawid D Salomatina Oksana V OV Salakhutdinov Nariman F NF Zenkova Marina A MA Logashenko Evgeniya B EB
Scientific reports 20171025 1
Highly pathogenic influenza viruses pose a serious public health threat to humans. Although vaccines are available, new antivirals are needed to efficiently control disease progression and virus transmission due to the emergence of drug-resistant viral strains. In this study, we describe the anti-viral properties of Soloxolone methyl (SM) (methyl 2-cyano-3,12-dioxo-18βH-olean-9(11),1(2)-dien-30-oate, a chemical derivative of glycyrrhetinic acid) against the flu virus. Anti-flu efficacy studies r ...[more]