Ontology highlight
ABSTRACT:
SUBMITTER: Martins RM
PROVIDER: S-EPMC5656681 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Martins Rafael M RM Macpherson Cameron R CR Claes Aurélie A Scheidig-Benatar Christine C Sakamoto Hiroshi H Yam Xue Yan XY Preiser Peter P Goel Suchi S Wahlgren Mats M Sismeiro Odile O Coppée Jean-Yves JY Scherf Artur A
Scientific reports 20171025 1
Variegated surface antigen expression is key to chronic infection and pathogenesis of the human malaria parasite Plasmodium falciparum. This protozoan parasite expresses distinct surface molecules that are encoded by clonally variant gene families such as var, rif and stevor. The molecular mechanisms governing activation of individual members remain ill-defined. To investigate the molecular events of the initial transcriptional activation process we focused on a member of the apicomplexan ApiAP2 ...[more]