Ontology highlight
ABSTRACT:
SUBMITTER: Hagbom M
PROVIDER: S-EPMC5659648 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Hagbom Marie M Novak Daniel D Ekström Malin M Khalid Younis Y Andersson Maria M Lindh Magnus M Nordgren Johan J Svensson Lennart L
PloS one 20171027 10
<h4>Background</h4>Rotavirus and norovirus cause acute gastroenteritis with severe diarrhoea and vomiting, symptoms that may lead to severe dehydration and death. The objective of this randomized double-blinded placebo-controlled study was to investigate whether ondansetron, a serotonin receptor antagonist could attenuate rotavirus- and norovirus-induced vomiting and diarrhoea, which would facilitate oral rehydration and possibly accelerate recovery and reduce need for hospitalization.<h4>Method ...[more]