Ontology highlight
ABSTRACT:
SUBMITTER: Yoon YG
PROVIDER: S-EPMC5660712 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Yoon Young-Gyu YG Dai Peilun P Wohlwend Jeremy J Chang Jae-Byum JB Marblestone Adam H AH Boyden Edward S ES
Frontiers in computational neuroscience 20171024
We here introduce and study the properties, via computer simulation, of a candidate automated approach to algorithmic reconstruction of dense neural morphology, based on simulated data of the kind that would be obtained via two emerging molecular technologies-expansion microscopy (ExM) and <i>in-situ</i> molecular barcoding. We utilize a convolutional neural network to detect neuronal boundaries from protein-tagged plasma membrane images obtained via ExM, as well as a subsequent supervoxel-mergi ...[more]