Adder and a coarse-grained approach to cell size homeostasis in bacteria.
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ABSTRACT:
SUBMITTER: Sauls JT
PROVIDER: S-EPMC5660915 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Publications
Adder and a coarse-grained approach to cell size homeostasis in bacteria.
Sauls John T JT Li Dongyang D Jun Suckjoon S
Current opinion in cell biology 20160220
Cell size control and homeostasis is a long-standing subject in biology. Recent experimental work provides extensive evidence for a simple, quantitative size homeostasis principle coined adder (as opposed to sizer or timer). The adder principle provides unexpected insights into how bacteria maintain their size without employing a feedback mechanism. We review the genesis of adder and recent cell size homeostasis study on evolutionarily divergent bacterial organisms and beyond. We propose new coa ...[more]
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