Ontology highlight
ABSTRACT:
SUBMITTER: Anand S
PROVIDER: S-EPMC5662603 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Anand Sanjay S Desai Vidhi V Alsmadi Nesreen N Kanneganti Aswini A Nguyen Dianna Huyen-Tram DH Tran Martin M Patil Lokesh L Vasudevan Srikanth S Xu Cancan C Hong Yi Y Cheng Jonathan J Keefer Edward E Romero-Ortega Mario I MI
Scientific reports 20171030 1
Neural interfaces are designed to decode motor intent and evoke sensory precepts in amputees. In peripheral nerves, recording movement intent is challenging because motor axons are only a small fraction compared to sensory fibers and are heterogeneously mixed particularly at proximal levels. We previously reported that pain and myelinated axons regenerating through a Y-shaped nerve guide with sealed ends, can be modulated by luminar release of nerve growth factor (NGF) and neurotrophin-3 (NT-3), ...[more]