Ontology highlight
ABSTRACT:
SUBMITTER: Podd BS
PROVIDER: S-EPMC5663307 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Podd Bradley S BS Simon Dennis W DW Lopez Santiago S Nowalk Andrew A Aneja Rajesh R Carcillo Joseph A JA
Pediatric clinics of North America 20170818 5
Adjunctive therapies have been proposed for use in at least 5 inflammation pathobiology phenotypes in pediatric sepsis-induced multiple organ failure. This article discusses host-pathogen interaction prototypes to facilitate understanding of the rationale for personalized therapy in these phenotypes. The article discusses the literature on adjunctive antiinflammatory and immune modulation therapies that, in addition to traditional organ support and infection source control, might be part of a pe ...[more]