Ontology highlight
ABSTRACT:
SUBMITTER: Lamb LE
PROVIDER: S-EPMC5663335 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Lamb Laura E LE Janicki Joseph J JJ Bartolone Sarah N SN Peters Kenneth M KM Chancellor Michael B MB
PloS one 20171031 10
<h4>Background</h4>Interstitial cystitis/bladder pain syndrome (IC) is a multifactorial syndrome of severe pelvic and genitalia pain and compromised urinary function; a subset of IC patients present with Hunner's lesions or ulcers on their bladder walls (UIC). UIC is diagnosed by cystoscopy, which may be quite painful. The objective of this study was to determine if a calculated Bladder Permeability Defect Risk Score (BP-RS) based on non-invasive urinary cytokines could discriminate UIC patients ...[more]