Dataset Information

Prevalence and risk factors of eye diseases in adult patients with obstructive sleep apnoea: results from the SLE.E.P.Y cohort study.

ABSTRACT:

Objectives

To assess the occurrence of glaucoma, eyelid, corneal and macular disorders in a cohort of patients with obstructive sleep apnoea (OSA) diagnosed by overnight polysomnography and to investigate into the risk factors for the above eye diseases (EDs).

Design

Cross-sectional cohort study between 2014 and 2015.

Setting

Unit of Respiratory Medicine and Eye Clinic of the University of Verona.

Participants

431 consecutive patients were considered eligible. Of these, 87 declined to participate, 35 were untraceable and 13 were deceased.

Interventions

A complete ophthalmic evaluation of both eyes for each patient.

Primary and secondary outcome measures

Best-corrected distance visual acuity, intraocular pressure, corneal, macular and optic nerve optical coherence tomography, ocular aberrometry, optic nerve laser polarimetry, visual field test, and eyelid examination.

Results

296 patients aged 64.5±12.8 years, 23% female and 77% male, underwent ophthalmic examination. There was 56% (n=166) prevalence of eyelid disorders, 27% (n=80) of corneal disorders, 13% (n=39) of macular disorders and 11% (n=33) of glaucoma. Advancing age was not associated with the severity of OSA, while significant differences were found for gender, body mass index, Oxygen Desaturation Index, smoking habit, hypertension and diabetes. Severe OSA was significantly associated with glaucoma (OR, 95% CI 1.05 to 5.93, p=0.037).

Conclusions

EDs were more prevalent in our patinets with OSA than in the general population. Severe Apnoea/Hypopnoea Index level seemed to play a role as risk factor only for glaucoma.

SUBMITTER: Pedrotti E

PROVIDER: S-EPMC5665218 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature

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Publications

Prevalence and risk factors of eye diseases in adult patients with obstructive sleep apnoea: results from the SLE.E.P.Y cohort study.

Pedrotti Emilio E Demasi Christian Luigi CL Bruni Enrico E Bosello Francesca F Di Sarro Paolo Plinio PP Passilongo Mattia M Fasolo Adriano A Gennaro Nicola N De Gregorio Alessandra A Ferrari Marcello M Marchini Giorgio G

BMJ open 20171022 10

<h4>Objectives</h4>To assess the occurrence of glaucoma, eyelid, corneal and macular disorders in a cohort of patients with obstructive sleep apnoea (OSA) diagnosed by overnight polysomnography and to investigate into the risk factors for the above eye diseases (EDs).<h4>Design</h4>Cross-sectional cohort study between 2014 and 2015.<h4>Setting</h4>Unit of Respiratory Medicine and Eye Clinic of the University of Verona.<h4>Participants</h4>431 consecutive patients were considered eligible. Of the ...[more]

PMID: 29061607

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Dataset Information

Prevalence and risk factors of eye diseases in adult patients with obstructive sleep apnoea: results from the SLE.E.P.Y cohort study.

Objectives

Design

Setting

Participants

Interventions

Primary and secondary outcome measures

Results

Conclusions

Publications

Prevalence and risk factors of eye diseases in adult patients with obstructive sleep apnoea: results from the SLE.E.P.Y cohort study.

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