Ontology highlight
ABSTRACT:
SUBMITTER: Nakamoto S
PROVIDER: S-EPMC5666539 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Nakamoto Shingo S Imazeki Fumio F Kanda Tatsuo T Wu Shuang S Nakamura Masato M Yasui Shin S Tawada Akinobu A Mikata Rintaro R Chiba Tetsuhiro T Arai Makoto M Yokosuka Osamu O Shirasawa Hiroshi H
International journal of medical sciences 20170904 11
<h4>Background</h4>Genetic variation near the interferon lambda 3 (<i>IFNL3</i>) is known to be associated with response to pegylated interferon (pegIFN) and ribavirin combination therapy in patients with chronic hepatitis C virus (HCV) infection which is often accompanied by hepatic steatosis.<h4>Aims</h4>We examined whether this genetic variation is associated with host lipids and treatment response.<h4>Methods</h4>A total of 101 Japanese patients who had underwent liver biopsy before treatmen ...[more]