Ontology highlight
ABSTRACT:
SUBMITTER: Stephenson-Brown A
PROVIDER: S-EPMC5666680 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Stephenson-Brown Alexander A Acton Aaron L AL Preece Jon A JA Fossey John S JS Mendes Paula M PM
Chemical science 20150617 9
Many glycoproteins are intimately linked to the onset and progression of numerous heritable or acquired diseases of humans, including cancer. Indeed the recognition of specific glycoproteins remains a significant challenge in analytical method and diagnostic development. Herein, a hierarchical bottom-up route exploiting reversible covalent interactions with boronic acids and so-called click chemistry for the fabrication of glycoprotein selective surfaces that surmount current antibody constraint ...[more]