Ontology highlight
ABSTRACT:
SUBMITTER: Siu LL
PROVIDER: S-EPMC5669041 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Siu Lillian L LL Ivy S Percy SP Dixon Erica L EL Gravell Amy E AE Reeves Steven A SA Rosner Gary L GL
Clinical cancer research : an official journal of the American Association for Cancer Research 20170901 17
Immunotherapy adds an exciting new dimension to the treatment of cancer, joining other approaches as a key pillar in the oncotherapeutics armamentarium. Immuno-oncology agents harbor unique mechanisms of antitumor activity by leveraging the host immune system, which may result in response patterns, resistance kinetics, and toxicity profiles that differ from other systemic therapies. These features have led to many discussions on ways to optimally integrate immunotherapy into cancer clinical tria ...[more]