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An efficient synthesis of a C12-higher sugar aminoalditol.

ABSTRACT: The C12-aminoalditol H2NCH2-(CHOBn)10-CH2OH was prepared from two simple monosaccharide building blocks. The synthesis was realized by a regioselective introduction of the azide group and subsequent protection-deprotection transformations. The chemical reactivity of the aminoalditol was tested in the reductive amination reaction with a selectively protected sucrose monoaldehyde.

SUBMITTER: Szyszka L

PROVIDER: S-EPMC5669227 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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An efficient synthesis of a C12-higher sugar aminoalditol.

Szyszka Łukasz Ł Osuch-Kwiatkowska Anna A Potopnyk Mykhaylo A MA Jarosz Sławomir S

Beilstein journal of organic chemistry 20171016

The C12-aminoalditol H2NCH2-(CHOBn)10-CH2OH was prepared from two simple monosaccharide building blocks. The synthesis was realized by a regioselective introduction of the azide group and subsequent protection-deprotection transformations. The chemical reactivity of the aminoalditol was tested in the reductive amination reaction with a selectively protected sucrose monoaldehyde. ...[more]

PMID: 29114320

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