Ontology highlight
ABSTRACT:
SUBMITTER: Azmi AS
PROVIDER: S-EPMC5669877 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Azmi Asfar S AS Li Yiwei Y Muqbil Irfana I Aboukameel Amro A Senapedis William W Baloglu Erkan E Landesman Yosef Y Shacham Sharon S Kauffman Michael G MG Philip Philip A PA Mohammad Ramzi M RM
Oncotarget 20170717 47
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer related deaths in the United States with a majority of these patients dying from aggressively invasive and metastatic disease. There is growing evidence that suggests an important role for microRNAs (miRNAs) in the pathobiology of aggressive PDAC. In this study, we found that the expression of miR-145 was significantly lower in PDAC cells when compared to normal pancreatic duct epithelial cells. Here we show that inhibi ...[more]