Ontology highlight
ABSTRACT:
SUBMITTER: Gupta S
PROVIDER: S-EPMC5671433 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Gupta Sonali S Tewatia Parul P Misri Jyoti J Singh Rajni R
Indian journal of microbiology 20170926 4
Present study demonstrated the expression of cloned <i>Bacillus subtilis</i> RSE163 keratinase gene and in silico binding affinities of deduced protein with psoriasis topical drugs for systemic absorption and permeation through skin. The <i>ker</i> gene expressed in <i>E. coli</i> showed significantly higher keratinase activity 450 ± 10.43 U representing 1342 bp nucleotides encoding 447 amino acids with molecular weight of 46 kDa. The modeled structure was validated using ramachandran's plot sho ...[more]