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Focused Review: Cytotoxic and Antioxidant Potentials of Mangrove-Derived Streptomyces.


ABSTRACT: Human life expectancy is rapidly increasing with an associated increasing burden of chronic diseases, such as neurodegenerative diseases and cancer. However, there is limited progress in finding effective treatment for these conditions. For this reason, members of the genus Streptomyces have been explored extensively over the past decades as these filamentous bacteria are highly efficient in producing bioactive compounds with human health benefits. Being ubiquitous in nature, streptomycetes can be found in both terrestrial and marine environments. Previously, two Streptomyces strains (MUSC 137T and MUM 256) isolated from mangrove sediments in Peninsular Malaysia demonstrated potent antioxidant and cytotoxic activities against several human cancer cell lines on bioactivity screening. These

SUBMITTER: Ser HL 

PROVIDER: S-EPMC5672783 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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