Ontology highlight
ABSTRACT:
SUBMITTER: Chen YY
PROVIDER: S-EPMC5673492 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Chen Yi-Yung YY Powell Theresa L TL Jansson Thomas T
Molecular and cellular endocrinology 20161209
Vitamin D deficiency during pregnancy is linked to adverse perinatal outcomes such as small for gestational age infants. Recent evidence suggests that changes in placental amino acid transport contribute to altered fetal growth. We tested the hypothesis that 1,25-dihydroxy vitamin D<sub>3</sub> increases the gene expression of System A and L amino acid transporter isoforms and stimulates placental amino acid transport activity in cultured primary human trophoblast cells mediated by mTOR signalin ...[more]