Dataset Information
Green synthesis of capped gold nanoparticles and their effect on Gram-positive and Gram-negative bacteria.
Ontology highlight
ABSTRACT: Aim
We report synthesis of capped gold nanoparticles (C-AuNPs) of ?20-30 nm by reducing HAuCl4 with flower and leaf extracts of Ocimum tenuiflorum, leaves of Azadirachta indica and Mentha spicata and peel of Citrus sinensis plants.Methods
Atomic force microscopy (AFM) and transmission electron microscopy (TEM) determined their size, shape and topographical structures. The C-AuNPs with UV-Vis spectrophotometer produced a maximum absorption within 530-535 nm wavelengths. Their Fourier transform IR stretching frequencies, from 450 to 4000 cm-1, have inferred HAuCl4 reduction to Au.Results
The 512 and 600 ?gml-1 C-AuNP MICs were expressed on antimicrobial strains Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae, respectively.Conclusion
The chosen plant extracts have reduced the Au3+ to Au0 with simultaneous in situ capping with bacteria inhibiting activities. Green routes for C-AuNP synthesis could be an asset for several other biomedical and bioengineering applications.
SUBMITTER: Rao Y
PROVIDER: S-EPMC5674245 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Green synthesis of capped gold nanoparticles and their effect on Gram-positive and Gram-negative bacteria.
Future science OA 20170905 4
<h4>Aim</h4>We report synthesis of capped gold nanoparticles (C-AuNPs) of ≈20-30 nm by reducing HAuCl<sub>4</sub> with flower and leaf extracts of <i>Ocimum tenuiflorum</i>, leaves of <i>Azadirachta indica</i> and <i>Mentha spicata</i> and peel of <i>Citrus sinensis</i> plants.<h4>Methods</h4>Atomic force microscopy (AFM) and transmission electron microscopy (TEM) determined their size, shape and topographical structures. The C-AuNPs with UV-Vis spectrophotometer produced a maximum absorption wi ...[more]